Study of geometrical model of wound regeneration in New Zealand rabbit

ABSTRACT

One of the best examples of epimorphic regeneration in the mammals is the formation of new tissues formed from blastema in holes punched in the ears of rabbits. The aim of this research is to investigate speed and percentage of regeneration in different geometrical shaped holes and different regions of rabbit's ear. In this experimental research different region of rabbit's ear [proximal, medial and distal] were punched as different geometrical shaped holes [circle, quadrangle and triangle] with the same area [50 mm[2]] Ubyg a puncher which designed for this purpose. The regeneration of wounds was evaluated and the percentage of regeneration was calculated. After punching, each 3 days [36-40 days]. Results showed speed and percentage of regeneration in circular holes was significantly [P < 0.05] more than quadrangular and triangular holes. In addition, regeneration speed of holes located in proximal regions of ear, was more than peripheral holes. Wound regeneration in rabbit's ear is related to the geometrical shape of holes. Speed and the percentage of regeneration in circular shapes is more than angular shapes