Hyperglycemia and mortality in critically ill patients
Pakistan Journal of Medical Sciences. 2009; 25 (2): 232-237
Dans Anglais
| IMEMR
| ID: emr-92409
ABSTRACT
To analyze the relation between serum glucose concentration and hospital outcome across the critically ill patients. A single-centre, retrospective study was performed at surgical and medical intensive care unit. Admission glucose, mean morning glucose, mean glucose, maximal glucose and time-averaged glucose levels were calculated for each patient. The time-averaged hyperglycemia was defined as the area under the curve above the upper limit of normal, divided by the total length of stay. Of 300 patients with a median stay of 16 days, the mortality rate was 32%. Mean fasting glucose was 121 mg/dl in survivors versus 160 mg/dl in non survivors [P=0.001]. Mean admission glucose was 127 mg/dl in survivors versus 142 mg/dl in non survivors [0.03]. Median time-averaged hyperglycemia was 4 mg/dl in survivors versus 17.5 mg/dl in nonsurvivors [P < 0.006]. The area under the receiver operator characteristic [ROC] curve was 0.59 for time-averaged glucose and 0.73 for mean fasting glucose. Whereas time-averaged hyperglycema is a useful assessment for glucose control in critically ill patients, it has no priority to admission glucose and mean fasting glucose for outcome prediction
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Indice:
Méditerranée orientale
Sujet Principal:
Glycémie
/
Taux de survie
/
Études rétrospectives
/
Mortalité
/
Résultat thérapeutique
/
Maladie grave
/
Unités de soins intensifs
/
Durée du séjour
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Pak. J. Med. Sci.
Année:
2009
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