JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 1996; 6 (4): 201-4
Dans Anglais
| IMEMR
| ID: emr-95985
ABSTRACT
The effect of serotonin on gastric acid secretion and its acidity have been examined by using four hour pylorus ligated rats of different age groups. Serotonin alone decreased the volume of gastric secretion and, free and total acidity in both younger and older animals, while methylsergide alone increased these parameters. Each of these drugs produced a significantly higher response in older animals. Methylsergide when given with serotonin abolished the inhibitory effect of serotonin and the observed secretions were similar to those of basal state. This indicates that serotonin as gastric inhibitor acts in accordance with parietal cell mass which increases with age
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Indice:
Méditerranée orientale
Sujet Principal:
Pylore
/
Rats
/
Acide gastrique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
J. Coll. Physicians Surg. Pak.
Année:
1996
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