Chemical castration in male rats with special reference to the micromorphological features of the sex organs

ABSTRACT

Sixty 6-month old male rats were classified into 15 groups and were intratesticularly injected with some necrotizing chemical agents including 3% and 5% formalin, different grades of glacial acetic acid either alone or with glycerol, alcohol 95% and 30% calcium chloride in 95% alcohol. At the end of the experiment, testes, epididymides, seminal vesicles and prostate gl and s were excised and histological sections were prepared. The results showed that the most effective irreversible degenerative changes in the testes and accessory gl and s were induced by 3% and 5% formalin, the different grades of glacial acetic acid and 30% calcium chloride in 95% alcohol. The clinicopathological results were assessed and thoroughly discussed with the other previous similar articles