Study of the thromboxane synthetasa inhibitory effect and antiplatelet action of levamisole
Arch. venez. farmacol. ter
;
10(2): 73-5, 1991. tab
Article
Dans Anglais
| LILACS
| ID: lil-105264
RESUMO
Thromboxane A* release by guinea pig lungs stimulated by AA and ionophore A 23187 was inhibited by levamisole (40 and 120 *g/ml), whereas leukotrienes, Pgl* or PgE* generation were unaffected. Since levamisole (1,5-25 *M) also inhibited plateled aggregation induced by collagen, which is markedly T x A* dependent, we suggest that levamisole acts as a thromboxane synthetase inhibitors
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Indice:
LILAS (Amériques)
Sujet Principal:
Lévamisole
langue:
Anglais
Texte intégral:
Arch. venez. farmacol. ter
Thème du journal:
Pharmacologie
/
Thérapeutique
Année:
1991
Type:
Article
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