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Study of the thromboxane synthetasa inhibitory effect and antiplatelet action of levamisole
Arch. venez. farmacol. ter ; 10(2): 73-5, 1991. tab
Article Dans Anglais | LILACS | ID: lil-105264
RESUMO
Thromboxane A* release by guinea pig lungs stimulated by AA and ionophore A 23187 was inhibited by levamisole (40 and 120 *g/ml), whereas leukotrienes, Pgl* or PgE* generation were unaffected. Since levamisole (1,5-25 *M) also inhibited plateled aggregation induced by collagen, which is markedly T x A* dependent, we suggest that levamisole acts as a thromboxane synthetase inhibitors
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Indice: LILAS (Amériques) Sujet Principal: Lévamisole langue: Anglais Texte intégral: Arch. venez. farmacol. ter Thème du journal: Pharmacologie / Thérapeutique Année: 1991 Type: Article

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Indice: LILAS (Amériques) Sujet Principal: Lévamisole langue: Anglais Texte intégral: Arch. venez. farmacol. ter Thème du journal: Pharmacologie / Thérapeutique Année: 1991 Type: Article