Toxic effects of ackee oil (Blighia sapida L) following subacute administration to rats
West Indian med. j
;
41(1): 23-6, Mar. 1992.
Article
Dans Anglais
| LILACS
| ID: lil-107504
RESUMO
Subacute intraperitoneal administration of the lipid portion of the unripe ackee arillus, referred to as "ackee oil", resulted in marked neutropenia (p<0.001) and increase in platelets (p<0.01) without anaemia, in rats. Blood urea, sodium amd aspartate aminotransferase levels were significantly decreased but glucose and bilirubin levels were similar to those of controls. The lungs showed areas of petechial haemorrhaghes and a dose-related perivascular and peribronchial mononuclear cell infiltration. The pulmonary toxicity may be interpreted as a hypersensitive reaction to ackee oil. Further research is in progress on the neutropenic effects of ackee oil.
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Indice:
LILAS (Amériques)
Sujet Principal:
Plantes comestibles
langue:
Anglais
Texte intégral:
West Indian med. j
Thème du journal:
Médicament
Année:
1992
Type:
Article
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