Human leukocyte a and B antigen, gene and haplotype frequencies in the population of the city of Säo Paulo in Brazil
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;25(1): 39-47, 1992. tab
Article
de En
| LILACS
| ID: lil-108998
Bibliothèque responsable:
BR26.1
RESUMO
Antigen, gene and haplotype frequencies are imnportant data for population analysis, poaternity exclusion testing, genetic studies, and for organ transplantation selection. We have studied the class I histocompatibility antigens of 617 unrelated individuals from the city of Säo Paulo, Brazil, to determine antigen and gene frequencies of HLA-A and 28 HLA-B antigens. Estimated haplotype frequencies were also determined, as well as the genetic distances of this population from European Caucasian and Negro populations. A previously unknown linkage disequilibrium was detected for A23-B49 and a clear trend towards antigen frequencies intermediate between Caucasoid and Negro populations was observed
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Indice:
LILACS
Sujet Principal:
Antigènes CD
/
Antigènes d'histocompatibilité
Limites du sujet:
Adult
/
Humans
Pays comme sujet:
America do sul
/
Brasil
langue:
En
Texte intégral:
Braz J Med Biol Res
/
Braz. j. med. biol. res
/
Braz. j. med. biol. res. (Online)
/
Brazilian journal of medical and biological research
/
Brazilian journal of medical and biological research (Impresso)
/
Rev. bras. pesqui. méd. biol
/
Revista brasileira de pesquisas médicas e biológicas
Thème du journal:
BIOLOGIA
/
MEDICINA
Année:
1992
Type:
Article