Structural features of LPPG and related compounds isolated from Trypanosoma cruzi trypomastigotes
Braz. j. med. biol. res
;
27(2): 227-31, Feb. 1994. ilus
Article
Dans Anglais
| LILACS
| ID: lil-138289
RESUMO
A hydrophobic fraction isolated from trypomastigotes of Trypanosoma cruzi is being characterized using immunological and chemical techniques. The lipopeptidophosphoglycan (LPPG) was identified in this fraction since it gave a positive reaction with anti-LPPG rabbit serum and had similar structural features such as the presence of ceramide as the lipid moiety, furanoic galactose, and a glycan moiety consistent with that obtained from an authentic sample of epimastigote LPPG, as judged by thin-layer chromatography. Furthermore, the hydrophobic fraction contained other glycolipids with different structural features. The lipid moiety of these compounds is alkylglycerol rather than a ceramide, the carbohydrate chain appears to be less complex than that in LPPG and no reactivity was observed towards an anti-LPPG serum
Recherche sur Google
Indice:
LILAS (Amériques)
Sujet Principal:
Phospholipides
/
Trypanosoma cruzi
/
Glycoconjugués
/
Peptidoglycane
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
1994
Type:
Article
/
Congrès et conférence
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS