Symptomatic environmental enteropathy in infancy: bacterial proliferation, funcional and morphological alterations of the small bowel
Rev. Hosp. Säo Paulo Esc. Paul. Med
;
4(1/4): 64-70, Dec. 1992. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-141166
RESUMO
Asymptomatic Environmental enteropathy may occur in the low social economic stratum of the population temporarily, thus contributing to marginal malnutrition. Bacterial proliferation in the upper portions of the small bowel may be responsible for alterations in the digestive-absorptive function leading to nutritional dwarfism. Forty infants of the Cidade Leonor slum who were under one year of age and presented with asymptomatic environmental enteropathy were investigated for digestive-absorptive function, bacterial proliferation in the small bowel lumen, and jejunal morphology. The mean value of the D-xylose absorption test was 21.0 ñ 10.0 mg per cent, significantly lower than controls (48.0 ñ 13.8 mg per cent) (p < 0.001). Bacterial proliferation in the small bowel of the colonic type was identified in 25 (62,5 per cent) of the infants and jejunal mucosa abnormalities were found in 29(72.5 per cent) of the specimens. Grade II villous atrophy was the most frequent alteration found. The inflammatory infiltration in the lamina propria increased in the total group, varying from light to severe. Alterations in the microecology of the small intestine can occur even in the absence of diarrhea. Therefore, the nonexistence of symptoms does not necessarily imply a condition of weillbeing. If true measures are proposed to improve the quality of life in these poor communities the whole infant population must be taken into account and not only the group with overt symptoms
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Indice:
LILAS (Amériques)
Sujet Principal:
Zones de pauvreté
/
Maladies intestinales
/
Intestin grêle
Type d'étude:
Etude diagnostique
Limites du sujet:
Femelle
/
Humains
/
Bébé
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. Hosp. Säo Paulo Esc. Paul. Med
Thème du journal:
Médicament
Année:
1992
Type:
Article
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