Capillaria hepatica: a cause of septal fibrosis of the liver
Mem. Inst. Oswaldo Cruz
;
88(3): 441-7, July-Sept. 1993. ilus
Article
Dans Anglais
| LILACS
| ID: lil-148799
RESUMO
Fine, long, fibrous septa were observed as a late change developing in the acinar zone III of the liver of rats experimentally infected with the helminth Capillaria hepatica. Hepatic septal fibrosis begun 30 days after inoculation of embryonated eggs into the stomach of rats and became clearly evident from the 40th day onwards. Experimental observation was undertaken for 170 days. Septal fibrosis increased progressively with time and was most marked when the parasitic nodules formed around larvae, disintegrating worms and eggs were involving. Septal fibrosis of the liver has not been previously recognized as a manifestation of hepatic capillariasis. The presence of sequestered parasite antigens, probably being slowly released within the liver, appears to be a major factor in the pathogenesis of hepatic septal fibrosis observed in rats with C. hepatica infection
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Capillaria
/
Cirrhose expérimentale
/
Parasitoses hépatiques
/
Nématodoses
Type d'étude:
Étude pronostique
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
1993
Type:
Article
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