The importance of molecular biology in hematologic disorders
Rev. Hosp. Säo Paulo Esc. Paul. Med
;
7(1/2): 7-17, Jan.-Jun. 1996. tab
Article
Dans Anglais
| LILACS
| ID: lil-201436
RESUMO
The advances in molecular biology and recombinant DNA technology have permitted the understanding of numerous diseases. Some of the earliest advances have occurred in the field of hematology when these approaches revealed genetic alterations in the hemoglobin gene of patients with sickle-cell anemia and thalassemias. In the field of onco-hematology, these powerful tools allowed to identify the chemical and biological changes that happen during the transformation of normal to malignant cells. Futhermore, it has led to the development of new agents for cancer therapy, such as interleukins and interferons. We describe here basic concepts of molecular biology, and the effect this technology had on the diagnostic capabilities for defining, diagnosing, and predicting the natural history of hematologic diseases.
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Indice:
LILAS (Amériques)
Sujet Principal:
Hémopathies
/
Biologie moléculaire
Type d'étude:
Etude diagnostique
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Rev. Hosp. Säo Paulo Esc. Paul. Med
Thème du journal:
Médicament
Année:
1996
Type:
Article
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