The stabilizing effects of the acquired immunity on the schistosomiasis transmission modeling - the sensitivity analysis
Mem. Inst. Oswaldo Cruz
; 93(supl.1): 63-73, Oct. 1998. tab, graf
Article
Dans En
| LILACS
| ID: lil-218644
Responsable en Bibliothèque :
BR15.1
RESUMO
A mathematical model is proposed to analyze the effects of acquired immunity on the transmission of schistosomiasis in the human host. From this model the prevalence curve dependent on four parameters can be obtained. These parameters were estimuted fitting the data by the maximum likehood method. The model showed a good retrieving capacity of real data from two endemic areas of schistosomiasis Touros, Brazil (Schistosoma mansoni) and Misungwi, Tanzania (S. haematobium). Also, the average worm burden per person and the dispersion of parasite per person in the community can be obtained from the model. In this paper, the stabilizing effects of the acquired immunity assumption in the model are assessed in terms of the epidemiological variables as follows. Regarded to the prevalence curve, we calculate the confidence interval, and related to the average worm burden and the worm dispersion in the community, the sensitivity analysis (the range of the variation) of both variables with respect to their parameters is performed.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Schistosomiase
/
Tanzanie
/
Brésil
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Humans
Pays comme sujet:
Africa
/
America do sul
/
Brasil
langue:
En
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
MEDICINA TROPICAL
/
PARASITOLOGIA
Année:
1998
Type:
Article
/
Congress and conference