Use of autologous fibrin glue in dermatologic surgery: application of skin graft and second intention healing
São Paulo med. j
;
116(4): 1747-52, jul.-ago. 1998. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-224902
RESUMO
Objective:
To evaluate the efficiency of biological sealant, an autologous fibrin glue, in dermatological surgery.Design:
Randomized clinical trialSetting:
The Dermatology Service of Hospital das Clinicas, Universidade de Campinas (UNICAMP), referral center. Patients 14 patients with malign epithelial cutaneoos tumors participated in the evaluation, each having two tumors, generally facial and symmetrical, in order to perform a comparative evaluation on the same individual. Procedures The glue was prepared beforehand with a sample of autologous blood. Surgical extirpation of the tumor was followed by grafts or second intention healing.Outcomes:
The efficiency of the sealant was then evaluated in relation to hemostasis, adhesion, surgical time and evolution of the granulation tissue, clinically and histologically.Results:
Immediate hemostasis and graft adhesion, with a significant reduction of surgical time, and in the open wounds there was immediate hemostasis and a clinical increase in granulation tissue, but with no histological differences among the groups on the 7th day.Conclusion:
It is an adjuvant resource in skin cancer surgery.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Tumeurs cutanées
/
Adhésifs tissulaires
/
Cicatrisation de plaie
/
Carcinome basocellulaire
/
Carcinome épidermoïde
/
Colle de fibrine
/
Transplantation de peau
Type d'étude:
Essai clinique contrôlé
/
Étude observationnelle
Limites du sujet:
Adulte
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
São Paulo med. j
Thème du journal:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Médicament
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Année:
1998
Type:
Article
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