Your browser doesn't support javascript.
loading
Distrofia muscular de Duchenne: efecto de la administración de vitamina E sobre la luminiscencia urinaria / Effects of vitamin E supplementation on urinary luminescence in patients with Duchenne muscular dystrophy
Rev. méd. Chile ; 126(10): 1165-72, oct. 1998. graf
Article Dans Espagnol | LILACS | ID: lil-242700
ABSTRACT

Background:

Urinary luminescence is increased in patients with Duchenne muscular dystrophy, probably due to the higher oxidative stress present in this disease.

Aim:

To assess the effects of vitamin E supplementation on urinary luminescence in children with Duchenne muscular dystrophy. Patients and

methods:

Eighteen children with muscular dystrophy aged 12.2 years old and nine control children aged 10 years old, received 400 IU/day of vitamin E during one month. Prior to supplementation and twice a week thereafter, spot urine samples were obtained to measure urinary luminescence in a scintillation counter.

Results:

There was a wide variability in urinary luminescence within and between children. Mean values decreased after vitamin E supplementation in six of nine controls and in 12 of 18 children with muscular dystrophy.

Conclusions:

Vitamin E supplementation significantly decreases urinary luminescence in healthy children and in patients with Duchenne muscular dystrophy. Therefore, it could be useful or the treatment of this disease
Sujets)
Recherche sur Google
Indice: LILAS (Amériques) Sujet Principal: Vitamine E / Mesures de luminescence / Dystrophies musculaires Type d'étude: Etude diagnostique Limites du sujet: Enfant / Humains / Mâle langue: Espagnol Texte intégral: Rev. méd. Chile Thème du journal: Médicament Année: 1998 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Recherche sur Google
Indice: LILAS (Amériques) Sujet Principal: Vitamine E / Mesures de luminescence / Dystrophies musculaires Type d'étude: Etude diagnostique Limites du sujet: Enfant / Humains / Mâle langue: Espagnol Texte intégral: Rev. méd. Chile Thème du journal: Médicament Année: 1998 Type: Article