Remisión parcial del hipercortisolismo en una enfermedad de Cushing posterior a una apoplejia hipofisiaria: caso clínico / Partial remission of Cushing disease after pituitary apoplexy: report of 1 case
Rev. méd. Chile
;
126(12): 1497-501, dic. 1998. ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-243748
ABSTRACT
ACTH secreting macroadenomas and pituitary apoplexy are unusual in Cushing disease. In the few cases reported in the literature, they have been found in long term hypercortisolism. We communicate a 43 yr old woman with a 4 year evolution Cushing syndrome, who developed sudden cephalea and oftalmoplejia. A Computed Tomography of the pituitary fossa disclosed a macroadenoma with intracapsular hemorrhage and suprasellar expansion. In the functional tests, serum cortisol was suppressed with dexamethasone in a dose of 1 and 8 mg and responded to the desmopressin stimulus. Nevertheless, cortisol levels were lower than those observed in Cushing syndrome of similar magnitude. The tumor was resected by transphenoidal surgery and immunohistochemistry to ACTH was positive. In this case, the laboratory results suggest a partial remission of the hypercortisolism after pituitary apoplexy
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Indice:
LILAS (Amériques)
Sujet Principal:
Tumeurs de l'hypophyse
/
Apoplexie hypophysaire
/
Syndrome de Cushing
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
1998
Type:
Article
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