Exposición crónica a plomo ambiental en lactantes chilenos II: efectos en el desarrollo psicomotor / Effects of chronic lead exposure on neurobehavioral development of Chilean lactating children
Rev. méd. Chile
;
127(1): 28-37, ene. 1999. ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-243755
ABSTRACT
Background:
Lactating children are specially susceptible to lead toxicity due to their underdeveloped nervous system, lower body mass, higher intestinal absorption and lower elimination rates.Aim:
To determine the effects of lead exposure, comparing Chilean lactating children residing in rural areas with low lead exposure, and in urban areas with high lead exposure. Material andmethods:
Newborns from public maternity hospitals of the rural locality of San Felipe and from Metropolitan Santiago, were recruited for the study. On admission to the study, umbilical cord and maternal blood samples were obtained and an inquiry about perinatal, sociohereditary and lead exposure history was done. Children were followed every 6 months until 24 months of age, measuring blood parameters and neurobehavioral development using Bayley scales.Results:
Three hundred twelve children from Santiago and 113 from San Felipe were studied. Maternal and children blood lead levels were higher in Santiago, but lower than those reported in other international studies. At 24 months of age, 4.5 percent of children from Santiago and 0.7 percent of children from San Felipe had levels over 10 µg/dl. No differences in neurobehavioral development were observed between children of both cities. At 24 months, scores of MDI scales were 91 in Santiago and 97 in San Felipe. The figures for PDI scale were 93 in Santiago and 93 in San Felipe. Main risk factors for a retarded neurobehavioral development were socioeconomic level with a mean Odds ratio of 3.5 (0.99-12.4), male sex with an Odds ratio of 2.3 (1.09-5.07) and stimulation at home with an Odds ratio of 0.7 (0.53-0.82.Conclusions:
In this cohort of children, no effect of lead levels on neurobehavioral development was found
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Indice:
LILAS (Amériques)
Sujet Principal:
Performance psychomotrice
/
Exposition environnementale
/
Intoxication par le plomb
Type d'étude:
Facteurs de risque
Limites du sujet:
Humains
/
Bébé
/
Nouveau-né
Pays comme sujet:
Amérique du Sud
/
Chili
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
1999
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Chili
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