Prospective evaluation of in vitro prodution of HIV-1 specific antibodies (IVAP), p24 antigenemia and viral culture for the diagnosis of HIV infection in children born to HIV-1 infected mothers
Braz. j. infect. dis
;
1(3): 131-4, Jun. 1997. tab
Article
Dans Anglais
| LILACS
| ID: lil-247328
RESUMO
Three methods (IVAP, p24 antigenemia and viral cultivatio) for the diagnosis of HIV-1 infection among children born to HIV-1 infected mothers were prospectively evaluated to determine the applicability of IVAP as a useful technique for that purpose. We tested 15 children (8p0 and 7 pII) and 19 adults with well-estabilished serological status for HIV infection. The children were followed for at least 1 year, unless they developed symptoms of clinical AIDS, or their HIV serology became negative. The IVAP method was more sensitive and specific than the other 2 tests in determining whether or not the infants were infected with HIV. All negative test results (5/8) were confirmed during the same time period. Despite the small sample studied, we conclude that IVAP is in inexpensive and simple technique potentially useful to establish whether or not HIV-seropositive children born to infected mothers are HIV infected.
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Indice:
LILAS (Amériques)
Sujet Principal:
Culture virale
/
Techniques in vitro
/
Sérodiagnostic du SIDA
/
Anticorps anti-VIH
/
Infections à VIH
/
Réaction de polymérisation en chaîne
/
VIH-1 (Virus de l'Immunodéficience Humaine de type 1)
/
Transmission verticale de maladie infectieuse
/
Production d'anticorps
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Bébé
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
1997
Type:
Article
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