Teste de tumorigenicidade em células vero / Tumorigenicity testing of vero cells
Arq. biol. tecnol
;
40(3): 596-600, out. 1997. tab
Article
Dans Portugais
| LILACS
| ID: lil-247536
RESUMO
Six-week-old athymic nude mices were used to test the capacity of Vero cell line to induce the tumor formation. KB cell line, obtained from human oral epidermoid carcinoma, was used as a positive test control. KB cell has proved to be a good positive control for tumorigenicity tests, since all the animals inoculated with this cell developed tumorous mass. These tumors started appearing in mice between 4th and 8 th days after inocullation, gradually progressed until reaching the maximal axes of 18 to 21 mm in the end of the test. None of the animals inoculated with Vero cells developed tumors in the test, demonstrating that way, that the Vero line at passages 145, 149 and 151 is not carcinogenic
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Indice:
LILAS (Amériques)
Sujet Principal:
Cellules Vero
/
Vaccins
/
Essaimage tumoral
/
Tumeurs
Limites du sujet:
Animaux
langue:
Portugais
Texte intégral:
Arq. biol. tecnol
Thème du journal:
Biologie
/
Biotechnologie
Année:
1997
Type:
Article
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