Spontaneous Kanamycin-resistant Escherichia coli mutant with altered periplasmic oligopeptide permease protein (OPPA) and impermeability to aminoglycosides
Rev. microbiol
;
30(2): 153-6, abr.-jun. 1999. ilus, tab
Article
Dans Portugais, Anglais
| LILACS
| ID: lil-257213
ABSTRACT
A spontaneous kanamycin-resistant Escherichia coli mutant, showing cross resitance to five other aminoglycosides and absence of the OppA protein was isolated. [3H]- dihydrostreptomycin uptake is reduced in this mutant, implying that the oligopeptide transport system in involved in accumulation of aminoglucosides, although apparently not related with aminoglycoside permeability alteration due to bacterial adaptation to osmotic changes.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Oligopeptides
/
Protéines de transport membranaire
/
Résistance à la kanamycine
/
Protéines
/
Périplasme
/
Escherichia coli
/
Aminosides
langue:
Anglais
/
Portugais
Texte intégral:
Rev. microbiol
Thème du journal:
Microbiologie
Année:
1999
Type:
Article
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