El estudio HERS conmociona a la terapia de sustitución hormonal / HERS study disturbs hormonal replacement therapy
Rev. méd. Chile
;
128(1): 98-104, ene. 2000. ilus
Article
Dans Espagnol
| LILACS
| ID: lil-258094
RESUMO
Cardiovascular protection of hormonal replacement therapy was considered a fact. The effects of estrogens on lipid levels and vascular health gave biological support to estrogen cardioprotection. The recently published HERS study showing no protective effects of estrogen and progesterone replacement therapy on the risk of myocardial infarction or coronary deaths is provoking perplexity. These surprising results may have several causes such as the use of progesterone, the associated use of cardioprotective agents or the short observation period. However, the study results scope is rectricted to secondary prevention. These cannot be extrapolated to frequent conditions of postmenopausal women such as primary prevention or sequential schemes. Likewise, this investigation underscores the importance of a critical and continued evaluation of apparently well established therapeutic approaches
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Oestrogénothérapie substitutive
/
Post-ménopause
Limites du sujet:
Femelle
/
Humains
langue:
Espagnol
Texte intégral:
Rev. méd. Chile
Thème du journal:
Médicament
Année:
2000
Type:
Article
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