Factores de riesgo del cáncer de mama en mujeres de Santiago / Breast cancer risk factors in women from Santiago, Chile
Rev. méd. Chile
; 128(2): 137-43, feb. 2000. tab
Article
de Es
| LILACS
| ID: lil-258110
Bibliothèque responsable:
CL1.1
RESUMO
Background:
Epidemiological studies suggest a relation between breast cancer, diet and life styles.Aim:
To analyze the association between food patterns, obesity, smoking, alcohol consumption and breast cancer risk in women of Santiago. Patients andmethods:
A case-control study design (170 cases and 340 controls), matched by age and sex, was used. Through a food frequency questionnaire the average daily intake of vegetables, fruits, ß-carotene, vitamin A, C, E and fiber was analyzed. Other exposures to non-nutritional risks (parity, smoking, cancer history) were also studied. Conditional logistic regression was calculated to determine the odds ratio associated with variations in food and nutrient intake and nonnutritional factors.Results:
Cases had a greater BMI and a higher prevalence of obesity than controls (p< 0.02). No differences were observed in either group food patterns. The ORs for breast cancer associated with obesity and alcohol consumption were 1.65 (95 percent CI 1.06-2.64) and 1.61 (95 percent CI 1.06-2.54) respectively (p< 0.05). Multiparity had a protective effect with 0.66 less risk (95 percent CI 0.44-0.99). No protective effect associated to a greater intake of vegetables, fruits or natural antioxidants was observed. Multivariate analysis model disclosed obesity as a risk factor (OR 1.79, p< 0.02) and parity = 4 as protective (OR 0.62, p<0.02).Conclusions:
This study does not support a protective role for natural antioxidants against breast cancer but indicate a weakassociation with obesity
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Tumeurs du sein
Type d'étude:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Adult
/
Female
/
Humans
Pays comme sujet:
America do sul
/
Chile
langue:
Es
Texte intégral:
Rev. méd. Chile
Thème du journal:
MEDICINA
Année:
2000
Type:
Article
/
Project document