Study of Schistosoma mansoni isolates from patients with failure of treatment with oxamniquine
Mem. Inst. Oswaldo Cruz
;
95(3): 375-80, May-Jun. 2000. tab
Article
Dans Anglais
| LILACS
| ID: lil-258192
ABSTRACT
After three successive treatments with oxamniquine the continuing elimination of Schistosoma mansoni eggs was observed in patients, who came from various regions of Brazil, with different clinical forms of schistosomiasis. The objective of the present study was to determine the experimental behaviour of five different S. mansoni isolates in Swiss Webster mice that were submitted to treatment with the same drug. The experimental group with failure of treatment showed higher mean number of surviving male worms when it was compared to the group without failure of treatment. These date suggest the possibility of resistance to oxamniquine.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Oxamniquine
/
Schistosoma mansoni
/
Schistosomicides
/
Schistosomiase à Schistosoma mansoni
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2000
Type:
Article
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