Müllerian adenosarcoma of the uterus with sarcomatous overgrowth following tamoxifen treatment for breast cancer
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
55(1): 17-20, Jan.-Feb. 2000. ilus
Article
Dans Anglais
| LILACS
| ID: lil-260703
ABSTRACT
Müllerian adenosarcoma with sarcomatous overgrowth presented by a 52-year-old female patient after adjuvant tamoxifen treatment for breast carcinoma is described. The diagnosis was made on histological basis after curettage and complementary total hysterectomy with bilateral salpingo-oophorectomy. The immunohistochemical study showed high expression of estrogen receptors in the epithelial component of the lesion and irregularly positive findings in the stroma. The proliferative activity evaluated by Ki-67 immunoexpression was higher in the stroma than the epithelium. Some of the stromal cells showed rhabdomyoblastic differentiation. The association of tamoxifen use and development of mesenchymal neoplasms is discussed.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Tamoxifène
/
Tumeurs de l'utérus
/
Tumeurs du sein
/
Adénosarcome
/
Antinéoplasiques hormonaux
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Thème du journal:
Médicament
Année:
2000
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS