Cardiomiopatia arritimogênica do ventrículo direito. Valor preditivo da dispersäo do intervalo QT para avaliaçäo de risco arritmogênico e de morte súbita / Arrhythmogenic cardiomyopathy of the right ventricle. Predictive value of QT interval dispersion to assess arrhythmogenic risk and sudden death
Arq. bras. cardiol
;
75(2): 115-24, Aug. 2000. tab
Article
Dans Portugais, Anglais
| LILACS
| ID: lil-269931
ABSTRACT
OBJECTIVE:
To determine in arrhythmogenic right ventricular cardiomyopathy the value of QT interval dispersion for identifying the induction of sustained ventricular tachycardia in the electrophysiological study or the risk of sudden cardiac death.METHODS:
We assessed QT interval dispersion in the 12-lead electrocardiogram of 26 patients with arrhythmogenic right ventricular cardiomyopathy. We analyzed its association with sustained ventricular tachycardia and sudden cardiac death, and in 16 controls similar in age and sex.RESULTS:
(mean +/- SD). QT interval dispersion patients = 53.8+/-14.1ms; control group = 35.0+/-10.6ms, p=0.001. Patients with induction of ventricular tachycardia 52.5+/-13.8ms; without induction of ventricular tachycardia 57.5+/-12.8ms, p=0.420. In a mean follow-up period of 41+/-11 months, five sudden cardiac deaths occurred. QT interval dispersion in this group was 62.0+/-17.8, and in the others it was 51.9+/-12.8ms, p=0.852. Using a cutoff > or = 60ms to define an increase in the degree of the QT interval dispersion, we were able to identify patients at risk of sudden cardiac death with a sensitivity of 60 percent, a specificity of 57 percent, and positive and negative predictive values of 25 percent and 85 percent, respectively.CONCLUSION:
Patients with arrhythmogenic right ventricular cardiomyopathy have a significant increase in the degree of QT interval dispersion when compared with the healthy population. However it, did not identify patients with induction of ventricular tachycardia in the electrophysiological study, showing a very low predictive value for defining the risk of sudden cardiac death in the population studied.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Syndrome du QT long
/
Mort subite cardiaque
/
Tachycardie ventriculaire
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Dysplasie ventriculaire droite arythmogène
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
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Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
/
Portugais
Texte intégral:
Arq. bras. cardiol
Thème du journal:
Cardiologie
Année:
2000
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital PróCardíaco/BR
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