Pathophysiology of cancer cachexia
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
55(5): 181-93, Sept. 2000.
Article
Dans Anglais
| LILACS
| ID: lil-275171
ABSTRACT
Cancer cachexia is a frequent complication observed in patients with malignant tumors. Although several decades have passed since the first focus on the metabolic dysfunction's associated with cancer, few effective therapeutic interventions have been successfully introduced into the medical armamentarium. The present study thoroughly reviews the basic pathophysiology of cancer cachexia and the treatment options already investigated in that field. Experimental and clinical studies were evaluated individually in order to clarify the intricate alterations observed in tumor-bearing patients. The difficulties in introducing sound and effective nutritional support or metabolic manipulation to reverse cancer cachexia are outlined in this review.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Cachexie
/
Tumeurs
Type d'étude:
Revues systématiques évaluées
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Thème du journal:
Médicament
Année:
2000
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de Sao Paulo/BR
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