Hepatite aguda colestática pelo propiltiouracil. Relato de caso / Acute cholestatic hepatitis induced by propylthiouracil. case report
Arq. gastroenterol
;
37(2): 129-32, abr.-jun. 2000. ilus
Article
Dans Portugais
| LILACS
| ID: lil-279428
ABSTRACT
Propylthiouracil is widely used to treat patients with hyperthyroidism. However, propylthiouracil-induced hepatitis is an uncommon entity. The case of a 15-year-old boy treated with propylthiouracil for hyperthyroidism who developed a cholestatic acute hepatitis is reported. Viral, metabolic and autoimmune liver diseases were excluded and liver biopsy showed a pattern suggestive of drug-induced cholestatic hepatitis. After discontinuing the drug, there was a progressive resolution of symptoms and normalization of liver biochemical tests. Despite its rarity, patients receiving propylthiouracil are exposed to develop severe hepatotoxicity
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Propylthiouracile
/
Antithyroïdiens
/
Cholestase intrahépatique
/
Lésions hépatiques dues aux substances
Limites du sujet:
Adolescent
/
Humains
/
Mâle
langue:
Portugais
Texte intégral:
Arq. gastroenterol
Thème du journal:
Gastroentérologie
Année:
2000
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal do Paraná/BR
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