Biological characterization of Trypanosoma cruzi strains
Mem. Inst. Oswaldo Cruz
;
96(1): 53-59, Jan. 2001. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-281630
RESUMO
Biological parameters of five Trypanosoma cruzi strains from different sources were determined in order to know the laboratory behaviour of natural populations. The parameters evaluated were growth kinetics of epimastigotes, differentiation into metacyclic forms, infectivity in mammalian cells grown in vitro and parasite susceptibility to nifurtimox, benznidazole and gentian violet. Differences in transformation to metacyclic, in the percentage of infected cells as well as in the number of amastigotes per cell were observed among the strains. Regarding to pharmacological assays, Y strain was the most sensitive to the three assayed compounds. These data demonstrate the heterogeneity of natural populations of T. cruzi, the only responsible of infection in humans
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Trypanosoma cruzi
/
Génétique des populations
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2001
Type:
Article
Pays d'affiliation:
Espagne
Institution/Pays d'affiliation:
Universidad Autónoma de Madrid/ES
/
Universidad Complutense de Madrid/ES
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