Is the number of microembolic signals related to neurologic outcome in coronary bypass surgery?
Arq. neuropsiquiatr
; 59(1): 1-5, Mar. 2001. ilus, graf, tab
Article
de En
| LILACS
| ID: lil-284228
Bibliothèque responsable:
BR1.1
ABSTRACT
Coronary artery bypass surgery (CABG) without cardiopulmonary bypass (CPB) may potentially reduce the number of microembolic signals (MES) associated with aortic manipulation or generated by the pump circuit, resulting in a better neurologic outcome after surgery. Our aim was to compare the frequency of MES and neurologic complications in CABG with and without CPB. Twenty patients eligible to routine CABG without CPB were randomized to surgery with CPB and without CPB and continuously monitored by transcranial Doppler. Neurologic examination was performed in all patients before and after surgery. The two groups were similar with respect to demographics, risk factors, grade of aortic atheromatous disease and number of grafts. The frequency of MES in the nonCPB group was considerably lower than in CPB patients, however, we did not observe any change in the neurologic examination during the early postoperative period. Neurologic complications after CABG may be related to the size and composition of MES rather than to their absolute numbers. A large prospective multicentric randomized trial may help to elucidate this complex issue
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Pontage cardiopulmonaire
/
Pontage aortocoronarien
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Embolie intracrânienne
/
Complications peropératoires
Type d'étude:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Limites du sujet:
Female
/
Humans
/
Male
langue:
En
Texte intégral:
Arq. neuropsiquiatr
Thème du journal:
NEUROLOGIA
/
PSIQUIATRIA
Année:
2001
Type:
Article