Skin reactions to thimerosal and Leishmania in dogs from a leishmaniasis endemic area: it is better to keep them apart
Mem. Inst. Oswaldo Cruz
;
96(5): 679-681, July 2001. tab
Article
Dans Anglais
| LILACS
| ID: lil-289356
RESUMO
Positive Montenegro's skin test is a delayed type hypersensitivity reaction widely used as indicative of previous infection with Leishmania in both humans and dogs. Montenegro's antigen consists of a crude Leishmania antigen solution, usually containing thimerosal as preserving agent. In this work it is shown that a large proportion of dogs (11 out of 56) examined in an endemic area of leishmaniasis presented induration at the site of injection of a diluent containing thimerosal alone. This clearly demonstrates that thimerosal leads to a high number of false positive skin reactions in dogs and that its use in Montenegro's skin test antigenic preparations should be avoided
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Conservateurs pharmaceutiques
/
Peau
/
Thiomersal
/
Leishmaniose
/
Maladies des chiens
/
Leishmania
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2001
Type:
Article
/
descriptif de projet
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Centro de Referência em Doenças Endêmicas Pirajá da Silva/BR
/
Fundaçäo do Instituto Oswaldo Cruz/BR
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