Persistent asthma in adults: comparison of high resolution computed tomography of the lungs after one year of follow-up
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
56(3): 63-68, May-June 2001. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-298589
ABSTRACT
OBJECTIVE:
The aims of this study were to evaluate the role of high resolution computed tomography of the torax in detecting abnormalities in chronic asthmatic patients and to determine the behavior of these lesions after at least one year.METHOD:
Fourteen persistent asthmatic patients with a mean forced expiratory volume in 1-second that was 63 percent of predicted and a mean forced expiratory volume in 1-second /forced vital capacity of 60 percent had two high resolution computed tomographys separated by an interval of at least one year.RESULTS:
All 14 patients had abnormalities on both scans. The most common abnormality was bronchial wall thickening, which was present in all patients on both computed tomographys. Bronchiectasis was suggested on the first computed tomography in 5 of the 14 (36 percent) patients, but on follow-up, the bronchial dilatation had disappeared in 2 and diminished in a third. Only one patient had any emphysematous changes; a minimal persistent area of paraseptal emphysema was present on both scans. In 3 patients, a "mosaic" appearance was observed on the first scan, and this persisted on the follow-up computed tomography. Two patients had persistent areas of mucoid impaction. In a third patient, mucus plugging was detected only on the second computed tomography.CONCLUSIONS:
We conclude that there are many abnormalities on the high resolution computed tomography of patients with persistent asthma. Changes suggestive of bronchiectasis, namely bronchial dilatation, frequently resolve spontaneously. Therefore, the diagnosis of bronchiectasis by high resolution computed tomography in asthmatic patients must be made with caution, since bronchial dilatation can be reversible or can represent false dilatation. Nonsmoking chronic asthmatic subjects in this study had no evidence of centrilobular or panacinar emphysema
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Asthme
/
Tomodensitométrie
/
Poumon
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Thème du journal:
Médicament
Année:
2001
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
University of Säo Paulo/BR
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