Genotoxic evaluation of the effect of Thuya occidentalys tinctures

Valsa, J. O; Felzenszwalb, I

Valsa, J. O; Felzenszwalb, I.

Affiliation

Valsa, J. O; Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcantara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro. BR
Felzenszwalb, I; Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcantara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro. BR

Rev. bras. biol ; 61(2): 329-332, May 2001. tab

Article de En | LILACS | ID: lil-298650

Bibliothèque responsable: BR1.1

ABSTRACT

ABSTRACT

Three tinctures samples from extracts of the popular medicinal plant Thuya occidentalis were tested in vitro through two short term tests for measuring the activity of genotoxic chemicals. Using the Salmonella/mammalian-microsome (Mutatest) assay and the SOS-chromotest (induction of beta-galactosidase in Escherichia coli), none of the extract was effective in inducing mutagenesis or beta-galactosidase synthesis (as an indicator of general and early sign of DNA damage), even with metabolization

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Texte intégral: 1 Indice: LILACS Sujet Principal: Salmonella typhimurium / Extraits de plantes / Agents colorants / Escherichia coli / Tests de mutagénicité langue: En Texte intégral: Rev. bras. biol Thème du journal: BIOLOGIA Année: 2001 Type: Article

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