Vaccination against schistosomiasis and fascioliasis with the new recombinant antigen Sm14: potential basis of a multi-valent anti-helminth vaccine?
Mem. Inst. Oswaldo Cruz
;
90(2): 255-256, Mar.-Apr. 1995.
Article
Dans Anglais
| LILACS
| ID: lil-319898
ABSTRACT
Molecular cloning of components of protective antigenic preparations have suggested that related parasite fatty acid binding proteins could form the basis of the well documented protective, immune cross reactivity between the parasitic trematode worms Fasciola hepatica and Schistosoma mansoni. We have now confirmed the cross protective potential of parasite fatty acid binding proteins and suggest that it may be possible to produce a single vaccine that would be effective against at least two parasites, F. hepatica and S. mansoni of veterinary and human importance respectively.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Schistosoma mansoni
/
Schistosomiase à Schistosoma mansoni
/
Vaccins synthétiques
/
Vaccination
/
Fasciola hepatica
/
Fasciolase
/
Antigènes d'helminthe
Limites du sujet:
Animaux
/
Humains
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
1995
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Centro de Pesquisas René Rachou-FIOCRUZ/BR
/
Instituto Oswaldo Cruz/BR
/
Universidade Federal Rural do Rio de Janeiro/BR
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