Transmission blocking immunity as observed in a feeder system and serological reactivity to Pfs 48/45 and Pfs230 in field sera

Roeffen, W; Lensen, T; Mulder, B; Teelen, K; Sauerwein, R; Eling, W; Meuwissen, J. H; Beckers, P

Roeffen, W; Lensen, T; Mulder, B; Teelen, K; Sauerwein, R; Eling, W; Meuwissen, J. H; Beckers, P.

Roeffen, W; University of Nijmegen. Department of Medical Microbiology. NL
Lensen, T; University of Nijmegen. Department of Medical Microbiology. NL
Mulder, B; University of Nijmegen. Department of Medical Microbiology. NL
Teelen, K; University of Nijmegen. Department of Medical Microbiology. NL
Sauerwein, R; University of Nijmegen. Department of Medical Microbiology. NL
Eling, W; University of Nijmegen. Department of Medical Microbiology. NL
Meuwissen, J. H; University of Nijmegen. Department of Medical Microbiology. NL
Beckers, P; University of Nijmegen. Department of Medical Microbiology. NL

Mem. Inst. Oswaldo Cruz ; 89(Suppl.2): 13-15, 1994.

Article Dans Anglais | LILACS | ID: lil-319960

ABSTRACT

ABSTRACT

Monoclonal antibodies (mAbs) and human sera from gametocyte carriers were applied in the bio-assay to test for their transmission-blocking capacity. Competition ELISA's have been developed for the detection of natural transmission blocking antibodies. Approximately 55 of the sera blocking in the bio-assay gave positive results in these competition ELISA's.

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Test ELISA / Anticorps antiprotozoaires / Paludisme à Plasmodium falciparum / Sérums immuns / Antigènes de surface Limites du sujet: Adulte / Humains langue: Anglais Texte intégral: Mem. Inst. Oswaldo Cruz Thème du journal: Médecine tropicale / Parasitologie Année: 1994 Type: Article Pays d'affiliation: Pays-Bas Institution/Pays d'affiliation: University of Nijmegen/NL

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