Herpes simplex virus type 2 infection in pregnancy: asymptomatic viral excretion at delivery and seroepidemiologic survey of two socioeconomically distinct populations in São Paulo, Brazil
Rev. Inst. Med. Trop. Säo Paulo
;
35(3): 285-290, May-Jun. 1993.
Article
Dans Anglais
| LILACS
| ID: lil-320584
ABSTRACT
The objective of the present study was to estimate the prevalence of herpes simplex virus type 2 (HSV 2) antibodies in child bearing women of 2 Brazilian populations with different socioeconomic status and to determine the risk of neonatal HSV exposure by means of maternal cultures at the onset of labor. The study was conducted at 2 hospitals A, serving very low income patients and B, serving middle socioeconomic class. 173 participants from group A and 127 from B answered a questionnaire which showed that the patients had similar ages (27.7 and 26.8 years, respectively) but differed with regard to socioeconomic status, age at first intercourse (18.6 vs 20.6 years), number of sex partners (1.5 vs 1.2) and previous sexually transmitted diseases (15 vs. 1.5). History of genital herpes was given by 11 of group A participants and by a similar number, 7, of patients from group B. In addition, 200 serum samples from population A and 455 from B were tested by ELISA for anti HSV antibodies and 92 and 86, respectively, were found to be positive. Sixty seropositive samples from group A and 90 from B were further analyzed by Western blot, which showed the presence of type 2 specific antibodies in 46 and 36, respectively, suggesting an overall HSV 2 prevalence of 42 in group A and 31 in B. Cervical specimens were obtained for culture from 299 asymptomatic patients of population A and 313 of B. HSV was isolated from one specimen in each group, indicating a 0.3 incidence of asymptomatic viral excretion in both populations.(ABSTRACT TRUNCATED AT 250 WORDS)
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Complications infectieuses de la grossesse
/
Herpès génital
/
Herpèsvirus humain de type 2
Type d'étude:
Etude d'étiologie
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Nouveau-né
/
Grossesse
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. Inst. Med. Trop. Säo Paulo
Thème du journal:
Médecine tropicale
Année:
1993
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
HC-LIM-52 Virology Laboratory of the Institute of Tropical Medicine/BR
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