Hepatitis B vaccine--proposal for a standardized assessment of immune response
Rev. Inst. Med. Trop. Säo Paulo
;
34(2): 137-140, Mar.-Apr. 1992.
Article
Dans Anglais
| LILACS
| ID: lil-320621
ABSTRACT
The authors developed a comparative study of the various methods of assessment of immune response to Hepatitis B vaccine. Eighty-six health care professionals underwent a vaccination programme with three doses of plasma-derived vaccine against Hepatitis B (H-B-Vax, Merck, Sharp & Dohme) given intramuscularly. Assessment of immune response was carried out three months after the end of the programme, by radioimmunoassay (RIA) and enzyme immunoassay (EIA). The results showed that the semi-quantitative assessment of Anti-HBs antibodies by RIA or EIA was perfectly comparable to the reference method (quantitative determination of antibodies by RIA). In view of these findings, the authors suggest a standardization of assessment of immune response to the vaccine, thus permitting correct planning of booster doses and easier comparison between different studies.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Vaccins anti-hépatite B
/
Anticorps de l'hépatite B
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Rev. Inst. Med. Trop. Säo Paulo
Thème du journal:
Médecine tropicale
Année:
1992
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Escola Paulista de Medicina/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS