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Baypamun® action in hamsters experimentally infected with Leptospira interrogans serogroup Canicola
Langoni, Hélio; Seabra Junior, Rui; Cabral, Kenio Gouveia; Cunha, Eva Laurice Pereira.
  • Langoni, Hélio; Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Núcleo de Pesquisas em Zoonoses. Departamento de Higiene Veterinária e Saúde Pública. Botucatu. BR
  • Seabra Junior, Rui; s.af
  • Cabral, Kenio Gouveia; Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Area de Vigilância Sanitária. Botucatu. BR
  • Cunha, Eva Laurice Pereira; Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Area de Vigilância Sanitária. Botucatu. BR
Braz. j. vet. res. anim. sci ; 38(6): 293-295, 2001.
Article Dans Anglais | LILACS | ID: lil-324338
RESUMO
Baypamun® is an immunity modulator recommended as prophylactic and therapeutic use. In the present study, this product was used in the hamsters experimentally infected with Leptospira interrogans serogroup canicola. The animals were divided in 5 groups, with 20 animals each. This product was used as a therapeutic, prophylactic and as adjuvant. As a therapeutic use all the animals died. Despite of eight (40.0 percent) survivors, the prophylactic use wasn't also totally favorable due to leptospire recovering from kidneys of those animals. Based on the analysis of antibodies levels among animals that received vaccine and vaccine with Baypamun® as adjuvante, this product didn't conferred superior humoral answer. However, other studies should be accomplished utilizing this product in a longer period as well as verify the cellular answer by Baypamun® use as adjuvant in the infectious disease
Sujets)
Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Adjuvants immunologiques / Immunité / Leptospira interrogans Limites du sujet: Animaux langue: Anglais Texte intégral: Braz. j. vet. res. anim. sci Thème du journal: Médecine vétérinaire Année: 2001 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Estadual Paulista/BR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Adjuvants immunologiques / Immunité / Leptospira interrogans Limites du sujet: Animaux langue: Anglais Texte intégral: Braz. j. vet. res. anim. sci Thème du journal: Médecine vétérinaire Année: 2001 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Estadual Paulista/BR