Baypamun® action in hamsters experimentally infected with Leptospira interrogans serogroup Canicola
Braz. j. vet. res. anim. sci
;
38(6): 293-295, 2001.
Article
Dans Anglais
| LILACS
| ID: lil-324338
RESUMO
Baypamun® is an immunity modulator recommended as prophylactic and therapeutic use. In the present study, this product was used in the hamsters experimentally infected with Leptospira interrogans serogroup canicola. The animals were divided in 5 groups, with 20 animals each. This product was used as a therapeutic, prophylactic and as adjuvant. As a therapeutic use all the animals died. Despite of eight (40.0 percent) survivors, the prophylactic use wasn't also totally favorable due to leptospire recovering from kidneys of those animals. Based on the analysis of antibodies levels among animals that received vaccine and vaccine with Baypamun® as adjuvante, this product didn't conferred superior humoral answer. However, other studies should be accomplished utilizing this product in a longer period as well as verify the cellular answer by Baypamun® use as adjuvant in the infectious disease
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Adjuvants immunologiques
/
Immunité
/
Leptospira interrogans
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. j. vet. res. anim. sci
Thème du journal:
Médecine vétérinaire
Année:
2001
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Estadual Paulista/BR
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