Sensibilidad antimicrobiana y caracterización de cepas de Streptococcus pyogenes aisladas de un brote de escarlatina / Antimicrobial sensitivity and characterization of Streptococcus pyogenes strains isoleated from a scarlatina outbreak
Salud pública Méx
; 44(5): 437-441, sept.-oct. 2002.
Article
Dans Es
| LILACS
| ID: lil-331695
Responsable en Bibliothèque :
MX1.1
RESUMEN
OBJECTIVE:
To evaluate the in vitro activities of 13 antimicrobial agents against 47 group A Streptococcus pyogenes (GAS) strains, and to determine the presence of genes encoding streptococcal pyrogenic exotoxin A (SpeA) and the M-protein serotypes. MATERIALS ANDMETHODS:
A cross-sectional study was conducted at Centro de Salud Dr. JosÚ Castro Villagrana, during a scarlet fever outbreak occurring between December 1999 and January 2000, among 137 children at Colegio EspÝritu de AmÚrica. Minimum Inhibitory Concentrations (MICs) were obtained by the semiautomated microdilution method. Automated DNA sequencing was used for analysis of sequence variation in genes encoding the M protein, and SpeA.RESULTS:
All strains were sensitive to betalactams and clindamycin. Six (12.7) were resistant to erythromycin. The M2 type was the most frequently isolated GAS (27); almost all (96) bacteria with the SpeA gene had the gene encoding the M2 protein.CONCLUSIONS:
The recent resurgence of GAS infections calls for molecular epidemiology research and studies on the sensitivity to macrolides and beta-lactams.
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Scarlatine
/
Streptococcus pyogenes
/
Résistance aux substances
/
Épidémies de maladies
Type d'étude:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limites du sujet:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Pays comme sujet:
Mexico
langue:
Es
Texte intégral:
Salud pública Méx
Thème du journal:
SAUDE PUBLICA
Année:
2002
Type:
Article