Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis)
Rev. Soc. Bras. Med. Trop
;
35(4): 401-404, jul.-aug. 2002.
Article
Dans Anglais
| LILACS
| ID: lil-331739
ABSTRACT
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and culture supernatant, but negative in the cerebrospinal fluid. After three weeks of hospitalization the patient was discharged. No other infectious agent was detected in the blood and cerebrospinal fluid samples. The patient had full recovery from paralysis six months after the onset of DEN-2 infection.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Dengue
/
Virus de la dengue
/
Myélite transverse
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2002
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Ministério da Saúde/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR
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