Soroprevalência de anticorpos contra o antígeno CagA do Helicobacter pylori em pacientes com úlcera gástrica na regiÒo Norte do Brasil / Seroprevalence of antibodies against Helicobacter pylori CagA antigen in patients with gastric ulcer in the North region of Brazil
Rev. Soc. Bras. Med. Trop
;
35(4): 307-310, jul.-aug. 2002.
Article
Dans Portugais
| LILACS
| ID: lil-331752
ABSTRACT
Helicobacter pylori is a pathogenic agent with a worldwide distribution and is involved in the development of many gastrointestinal diseases. Nowadays infection with the virulent strain CagA+ of H. pylori is considered one of the main etiological factors in the development of gastric ulcer. Based on this information, we investigated the seroprevalence of virulent strains among patients with gastric ulcer from one region, using serologic tests to detect antibodies against H. pylori and CagA protein. Infection by the virulent strain was found in 82 (40/55) of the patients, and among these, 89 (40/45) presented an increased degree of inflammation in the gastric mucosa, with a dense infiltration of leukocytes in the tissue, which probably favored the formation of gastric ulcer. We concluded that the presence of the virulent strain is related to the development of an increased inflammation in the gastric mucosa.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Ulcère gastrique
/
Protéines bactériennes
/
Helicobacter pylori
/
Anticorps antibactériens
/
Antigènes bactériens
Limites du sujet:
Adulte
/
Aged80
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Portugais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2002
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital Ofir Loiola/BR
/
Universidade Federal do Pará/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS