Histometric study of socket healing after tooth extraction in rats treated with diclofenac
Braz. dent. j
;
13(2): 92-96, 2002.
Article
Dans Anglais
| LILACS
| ID: lil-332154
ABSTRACT
The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Extraction dentaire
/
Anti-inflammatoires non stéroïdiens
/
Diclofenac
/
Alvéole dentaire
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Braz. dent. j
Thème du journal:
Dentisterie
Année:
2002
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
University of São Paulo/BR
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