Human papillomavirus prevalence, viral load and cervical intraepithelial neoplasia in HIV-infected women
Braz. j. infect. dis
;
6(3): 129-135, Jun. 2002.
Article
Dans Anglais
| LILACS, SES-SP
| ID: lil-332322
ABSTRACT
HIV-infected women from S o Paulo city were enrolled in a cross-sectional study on Human Papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) prevalence and their association with laboratory markers of AIDS, namely HIV viral load and CD(4)(+) cell counts. A cervical specimen was collected and submitted to Hybrid Capture, a test for HPV viral load determination. HPV-DNA was detected in 173 of 265 women (64.5). Twenty (7.5) women were infected by one or more low-risk viruses, 89 (33) by one or more high-risk viruses, and 64 (24) harbored at least one HPV type from each risk group. Abnormal smears were observed in 19 of the patients, though there were no invasive carcinomas. Severely immunosuppressed patients (CD(4)/microL <100) were at the greatest risk of having a cytological abnormality and a high high-risk HPV viral load.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Infections à virus oncogènes
/
Infections à VIH
/
Tumeurs du col de l'utérus
/
Charge virale
/
Infections à papillomavirus
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Année:
2002
Type:
Article
Institution/Pays d'affiliation:
Casa da AIDS/BR
/
Digene do Brasil/BR
/
Emilio Ribas Institute/BR
/
Institute of Tropical Medicine/BR
/
University of São Paulo/BR
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