Human red blood cells from prenatal hemopoiesis. Lithium flux (sodium dependent) asymmetry
Biocell
;
24(3): 233-237, Dec. 2000.
Article
Dans Anglais
| LILACS
| ID: lil-335894
ABSTRACT
In red cells from umbilical cord blood it has been referred the existence of lithium fluxes (contralateral sodium dependent) asymmetry. On account of the relevancy of this transport system in some pathologies it is pertinent the study of its kinetics to relate normal with pathological states in which it is affected. Lithium fluxes--contralateral sodium dependent were determined in N-ethylmaleimide treated neonatal red blood cells. Experimental data were fitted by simple Michaelis-Menten kinetics, finding Km and Vmax variables. It was shown the persistency of asymmetry. The independence of sulfhydryl groups (or the occultation of the groups involved to this inhibitor) could explain asymmetry persistence.
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Indice:
LILAS (Amériques)
Sujet Principal:
Membrane cellulaire
/
Transport des ions
/
Sodium-Potassium-Exchanging ATPase
/
Érythrocytes
/
Lithium
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Anglais
Texte intégral:
Biocell
Thème du journal:
Clulas
Année:
2000
Type:
Article
Pays d'affiliation:
Argentine
Institution/Pays d'affiliation:
National University of Rosario/AR
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