Prevalence of antinuclear autoantibodies in the serum of normal blood dornors
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
;
58(6): 315-319, 2003. tab, graf
Article
Dans Anglais
| LILACS
| ID: lil-354165
RESUMO
OBJECTIVE:
To examine the presence of serum antinuclear autoantibodies in a healthy population.METHODS:
Serum of 500 normal blood donors between 18 and 60 years of age were tested for the presence of autoantibodies. Antinuclear antibodies were detected by indirect immunofluorescence technique using HEp-2 epithelial cells as the substrate. The presence of dnaN was detected by indirect immunofluorescence technique using Critidia lucillae as the substrate. Anti-SSA (RO), anti-SSB (LA), anti-Sm, and anti-RNP were determined by double radial immunodiffusion.RESULTS:
In the evaluation of the presence of serum antibodies, antinuclear antibodies were detected in 22.6 percent of the sera. The presence of other antibodies was not significant. The majority of the titers were 140.CONCLUSION:
The presence of autoantibodies is not necessarily pathologic and has to be related to the age group, gender, and clinical condition of the patient
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Autoanticorps
/
Anticorps antinucléaires
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Thème du journal:
Médicament
Année:
2003
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
University of Säo Paulo/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS