Papillary carcinoma of the thyroid in an autonomously functioning nodule
Arq. bras. endocrinol. metab
;
47(6): 739-743, dez. 2003. ilus
Article
Dans Anglais
| LILACS
| ID: lil-356029
ABSTRACT
The association of differentiated thyroid cancer and a functioning nodule is very low. We report on a case of papillary carcinoma in an autonomously functioning thyroid nodule in a 39 year-old female patient. The nodule extended to the whole right lobe and 131I scintigraphy has detected a "hot" nodule and a partial suppression of131I uptake in the left lobe. Serum TSH levels (RIA) were undetectable (<1.0µUI/mL), but total T3 (190ng/dL) and T4 (8.5µg/dL) were normal. The patient underwent a partial thyroidectomy and an adenomatous nodule was found with a small central nucleus (7mm) hosting a papillary carcinoma. Whole body scans detected only residual thyroid uptake and the patient was subsequently treated with 100mCi of 131I. The patient has been on replacement therapy with 150µg of L-thyroxine and free of tumor recurrence for 12 years after surgery. In conclusion:
the present report confirms other published cases in which the presence of a hot thyroid nodule does not exclude the concomitance of a well-differentiated thyroid carcinoma.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Tumeurs de la thyroïde
/
Carcinome papillaire
/
Maladie de Basedow
/
Nodule thyroïdien
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Arq. bras. endocrinol. metab
Thème du journal:
Endocrinologie
/
Métabolisme
Année:
2003
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital de Base do Distrito Federal/BR
/
Hospital de Taguatinga/BR
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