Extendidos delgados en la puncion aspiracion con aguja fina de tiroides: un estudio de 200 casos / Thin layer preparations in thyroid fine-needle aspiration: study of 200 cases
Rev. Fac. Cienc. Méd. (Córdoba)
;
60(2): 9-22, 2003. ilus, tab
Article
Dans Espagnol
| LILACS
| ID: lil-356901
ABSTRACT
INTRODUCTION:
Trying to increase the specificity and demonstrated sensibility of thyroid fine needle aspiration (TFNA) in the diagnosis of the thyroid nodule, and to improve the cytomorphologic diagnosis, we used the approach of realization of thin prep (TP), adapting the technique to the methods within our possibilities. MATERIALS ANDMETHODS:
The sample corresponded to a prospective study of 200 cases of material of thyroid nodules, obtained by means of ultrasonography guide fine needle aspiration, over a 30 month period. The study was carried out by means of conventional smear (CS) and TP, cytologic preparations were stained with hematoxilin-eosine (H-E), Papanicolaou (PAP) and Tint 15. The analysis of these same samples was carried out according to sex, age, characteristics of the nodules and cytomorphologic features.RESULTS:
The samples were satisfactory in 184 cases (92 per cent) and unsatisfactory in 16 cases (8 per cent). The prevalence in samples corresponded to the female sex (88.5 per cent). The pre-emptive diagnoses corresponded to Multinodular Goiter 41 (22.29 per cent)--Hashimoto's thyroiditis 4 (2.17 per cent)--Follicular lesions I 86(46.74 per cent), II 34 (18.47 per cent), III 6 (3.26 per cent)--Hurthle cell neoplasm 4 (2.17 per cent)--Papillary carcinoma 9 (4.90 per cent). The patient study was carried out according to the modified algorithm proposed by Gharib in 1997 and the Department of Cytology of the Karolinska Hospital of Stockholm (Sweden). The cytological diagnosis was compared to the final histological results.CONCLUSIONS:
The present work has demonstrated that even with the available methods, we have been able to carry out TP that were acceptable for its evaluation and with the same limitations of those obtained by CS, with respect to preparations dried in direct air and in the cases of non-conclusive diagnoses. We obtained a sensibility of 94.44 per cent and a specificity of 98.79 per cent.
Recherche sur Google
Indice:
LILAS (Amériques)
Sujet Principal:
Ponction-biopsie à l'aiguille
/
Nodule thyroïdien
/
Techniques de préparation histocytologique
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Espagnol
Texte intégral:
Rev. Fac. Cienc. Méd. (Córdoba)
Thème du journal:
Médicament
Année:
2003
Type:
Article
Pays d'affiliation:
Argentine
Institution/Pays d'affiliation:
Universidad Nacional de Cordoba/AR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS