Electrophoretic molecular karyotype of the dermatophyte Trichophyton rubrum
Genet. mol. biol
;
27(1): 99-102, 2004. ilus, tab
Article
Dans Anglais
| LILACS
| ID: lil-357880
RESUMO
The electrophoretic karyotype of the dermatophyte Trichophyton rubrum was established using contour-clamped homogeneous electric field (CHEF) gel electrophoresis. Five chromosomal bands of approximately 3.0 to 5.8 megabase pairs (Mbp) each were observed and together indicated that 22.05 Mbp of the total genome are organized as chromosomal macromolecules. In addition to establishing the number and size of T. rubrum chromosomes, these results open perspectives for the construction of chromosome-specific libraries and for the physical mapping of genes of interest, thus permitting future gene linkage studies in this pathogen. A detailed understanding of the karyotype and genomic organization of T. rubrum should contribute to further genetic, taxonomic and epidemiological studies of this dermatophyte.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Trichophyton
/
Cartographie chromosomique
/
Mycoses cutanées
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Genet. mol. biol
Thème du journal:
Génétique
Année:
2004
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de São Paulo/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS