Your browser doesn't support javascript.
loading
Behavior of cholinesterase and liver mitochondrial function in dogs submitted to normothermic ischemia and reperfusion
Fernandes, Luis Pinto; Sankarankutty, Ajith Kumar; Pacheco, Eduardo Garcia; Centurion, Sérgio; Jordani, Maria Cecília; Silva Júnior, Orlando de Castro e.
  • Fernandes, Luis Pinto; Universidade do Distrito Federal. Brasília. BR
  • Sankarankutty, Ajith Kumar; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Ribeirão Preto. BR
  • Pacheco, Eduardo Garcia; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Ribeirão Preto. BR
  • Centurion, Sérgio; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Ribeirão Preto. BR
  • Jordani, Maria Cecília; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Cirurgia e Anatomia. Ribeirão Preto. BR
  • Silva Júnior, Orlando de Castro e; s.af
Acta cir. bras ; 18(supl.5): 38-41, 2003. graf
Article Dans Anglais | LILACS | ID: lil-358583
ABSTRACT

Purpose:

The plasmatic activity of the cholinesterase (CHE) and the Tiver mitochondrial function, expressed by the ratio of respiratory control (RCR), were studied during normothermic ischemia.

Methods:

Sixteen adult mongrels, eight females and eight males were submitted to ischemia by clamping of the hepatic artery, portal vein and infrahepatic inferior vena cava, infra-hepatic, for two h, follwed by reperfusion for 1 h. The CHE and the mitochondrial function were evaluated at 60 and 120 min. of ischemia and at 15 and 60 minutes of reperfusion.

Results:

The CHE decreased, significandy, during ischemia and in reperfusion. The RCR was decreased at 120 min. of ischemia, returning to the initial values on reperfusion.

Conclusion:

In this study, the CHE was a sensitive indicator of ischemic injury , suggesting irreversibility of ischemia injury. The RCR, by other side, showed a greater sensibility than the CHE in detection sense, during the studied period, the reversibility of the hepatic ischemic injury.
Sujets)
Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Mitochondries du foie / Reperfusion / Cholinesterases / Ischémie Limites du sujet: Animaux langue: Anglais Texte intégral: Acta cir. bras Thème du journal: Chirurgie générale / Procedimentos Cir£rgicos Operat¢rios Année: 2003 Type: Article / descriptif de projet Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade de São Paulo/BR / Universidade do Distrito Federal/BR

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Mitochondries du foie / Reperfusion / Cholinesterases / Ischémie Limites du sujet: Animaux langue: Anglais Texte intégral: Acta cir. bras Thème du journal: Chirurgie générale / Procedimentos Cir£rgicos Operat¢rios Année: 2003 Type: Article / descriptif de projet Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade de São Paulo/BR / Universidade do Distrito Federal/BR