Effect of thiadiazine derivatives on intracellular amastigotes of Leishmania amazonensis
Mem. Inst. Oswaldo Cruz
;
99(3): 329-330, May 2004. ilus, graf
Article
Dans Anglais
| LILACS
| ID: lil-362004
RESUMO
Current therapy for leishmaniasis is not satisfactory. We describe the in vitro antiproliferative effects of new thiadiazine derivatives against Leishmania amazonensis. The compounds were found to be active against the amastigote form of the parasite, inhibiting parasite growing, from 10 to 89 percent, at a concentration of 100 ng/ml. This activity suggests that thiadiazine derivatives could be considered as potential antileishmanial compounds.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Thiadiazines
/
Leishmania brasiliensis
/
Antiprotozoaires
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2004
Type:
Article
Pays d'affiliation:
Cuba
Institution/Pays d'affiliation:
Instituto de Medicina Tropical Pedro Kourí/CU
/
Universidad de la Habana/CU
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