Leucemia Mielóide Aguda t(8; 21) após tratamento de hipertiroidismo com iodo radioativo: Leucemia secundária? / Acute Myeloid Leukemia t(8; 21) after treatment for hyperthyroidism using radioactive iodine: Secondary Leukemia?
Rev. bras. hematol. hemoter
;
24(2): 137-138, abr.-jun. 2002. ilus
Article
Dans Portugais
| LILACS
| ID: lil-365260
RESUMO
Acute leukemia following treatment with Iodine131 is a rare event. The possible carcinogenic effect of Iodine131 is still not clear and a large series of cases did not show an increased incidence of cancer. A case of AML t(8;21), three years after Iodine131 treatment for hyperthyroidism, is reported. Secondary AML with t(8;21) is described following exposure to drugs that target topoisomerase II and radiotherapy. The controversial potential of Iodine131 as a leukemogenic agent and the fact that t(8;21) is also found in de-novo AML, emphasize the problem in establishing a relationship between these events although this potential can not be ruled out.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Leucémie aigüe myéloïde
langue:
Portugais
Texte intégral:
Rev. bras. hematol. hemoter
Thème du journal:
Hématologie
Année:
2002
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de São Paulo/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS