Diffuse alveolar hemorrhage resulting from Pauci-immune pulmonary capillaritis
J. pneumol
;
29(4): 217-220, jul.-ago. 2003. ilus
Article
Dans Anglais
| LILACS
| ID: lil-366308
ABSTRACT
A 27 year-old female patient, cocaine user, presenting hemoptysis and progressive dyspnea with onset 48 hours prior to hospital admission, without any other signs or symptoms. Serum tests for infectious diseases, collagen disorders and vasculitis were negative. Urinalysis was normal. Computed tomography of the chest showed diffuse alveolar infiltrate, affecting mainly the lower left lobe. A thoracoscopic lung biopsy was performed to clarify the diagnosis. The histopathological findings showed capillaritis and diffuse intra-alveolar hemorrhage. Treated with steroid and cyclophosphamide pulse therapy, a good clinical and radiographical response was obtained. The recently described pauci-immune pulmonary capillaritis is characterized by the presence of isolated pulmonary capillaritis and negative serum testing for auto-immune diseases.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Méthylprednisolone
/
Cyclophosphamide
/
Glucocorticoïdes
/
Hémorragie
/
Immunosuppresseurs
/
Maladies pulmonaires
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
J. pneumol
Thème du journal:
Maladie pulmonaire (spécialité)
Année:
2003
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Barros Franco Clinic/BR
/
Hospital Municipal Miguel Couto/BR
/
National Institute for Cancer/BR
/
Pontifícia Universidade Católica do Rio de Janeiro/BR
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